New publication in British Medical - TopicsExpress

New publication in British Medical Journal heart.bmj/content/early/2013/07/30/heartjnl-2013-304262.abstract Heart doi:10.1136/heartjnl-2013-304262 Review Meta-analysis of secure randomised controlled trials of β-blockade to prevent perioperative death in non-cardiac surgery Conclusions Guideline bodies should retract their recommendations based on fictitious data without further delay. This should not be blocked by dispute over allocation of blame. The well-conducted trials indicate a statistically significant 27% increase in mortality from the initiation of perioperative β-blockade that guidelines currently recommend. Any remaining enthusiasts might best channel their energy into a further randomised trial which should be designed carefully and conducted honestly.

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