Researchers Link Gene to Increased Dendritic Spines; A Signpost of Autism By deleting the NrCAM gene, scientists have found a potential way to cut back on the neural connections implicated in Autism Spectrum Disorder. The research is in Journal of Neuroscience. (full access paywall) Research: “Neural Cell Adhesion Molecule NrCAM Regulates Semaphorin 3F-Induced Dendritic Spine Remodeling” by Galina P. Demyanenko, Vishwa Mohan, Xuying Zhang, Leann H. Brennaman, Katherine E.S. Dharbal, Tracy S. Tran, Paul B. Manis, and Patricia F. Maness in Journal of Neuroscience. doi:10.1523/JNEUROSCI.1774-14.2014 Image: A comparison of a dendrite with the protein NrCAM (top) and a dendrite without the protein (bottom), which has a greater density of spines that neurons use to form synaptic connections. Credit UNC Health Care. #neuroscience #autism #genetics
Posted on: Fri, 19 Sep 2014 21:03:23 +0000
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